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TP1288 |
Fertirelin
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Others
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Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist). |
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T1494 |
Alarelin Acetate
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Alarelin |
GNRH Receptor
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Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors. |
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T27837 |
Linzagolix
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GNRH Receptor
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Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,... |
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T5520 |
Cetrorelix Acetate
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Cetrorelix |
GNRH Receptor
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Cetrorelix Acetate is gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. |
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T4102 |
Goserelin acetate
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Fertilan,ICI-118630 acetate,Zoladex |
Apoptosis
,
GNRH Receptor
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Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer. |
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T11174 |
(R)-Elagolix
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NBI-56418 |
GNRH Receptor
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(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a do... |
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T5031 |
Elagolix sodium
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NBI-56418 sodium |
GNRH Receptor
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Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively). |
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T10217L |
Abarelix
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R3827,PPI 149 |
GNRH Receptor
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Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment. |
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T3630 |
Relugolix
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RVT-601,TAK-385 |
GNRH Receptor
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Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi... |
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T5520L |
Cetrorelix diacetate
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NS-75A,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate |
GNRH Receptor
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Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) ... |
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T17301 |
Opigolix
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Others
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Opigolix is a Gonadotropin-releasing hormone receptor antagonist. |
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T10988L |
Degarelix acetate(214766-78-6 free base)
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GNRH Receptor
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Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) . |
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TP2337 |
Ganirelix Acetate
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GNRH Receptor
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Ganirelix Acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist |
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TP1307 |
Buserelin Acetate (57982-77-1 free base)
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Buserelin Acetate |
GNRH Receptor
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Buserelin Acetate (57982-77-1 free base) (Buserelin Acetate) is an agonist of gonadotropin-releasing hormone receptor(GnRHR). |
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TP1896L1 |
Kisspeptin 234 acetate(1145998-81-7 free base)
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GPR
,
Kisspeptin
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Kisspeptin 234 acetate(1145998-81-7 free base) is a Kisspeptin receptor (KISS1, GPR54) antagonist; a Kisspeptin-10 analogue. It inhibits the stimulation of inositol phosphate (IP) (IC50 = 7 nM) and the release of gonadot... |
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T23412 |
T 98475
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Others
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gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally active |
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T10988 |
Degarelix
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GNRH Receptor
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Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist. |
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T10475 |
BAY-784
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Others
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BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R). |
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T76351 |
[D-Ala6]-LH-RH
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[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1]. |
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TP1936 |
RFRP-3(human)
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RFRP 3 (human) |
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Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons. |
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T76350 |
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
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[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH, a luteinizing hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor antagonist [1]. |
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T28795 |
SKI2496
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SKI 2496,SKI-2496 |
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SKI2496 is a potent and orally bioavailableantagonist of Gonadotropin-Releasing Hormone Receptor (hGnRHR IC50 = 0.46 nM; max. LH inh. inh. (%, h)= 84%, 12h; LH inh. (24h) = 76%.). SKI2496 exhibits more selective antagoni... |
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T70309 |
Dicetrorelix pamoate
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Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH)... |
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T76436 |
[MePhe7]-Neurokinin B
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|
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[MePhe7]-Neurokinin B is a neurokinin NK-3 receptor (NK3R) agonist, exhibiting a potent agonistic activity with an IC50 value of 3 nM. It acts as a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) s... |
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T68701 |
Abarelix acetate
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|
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Abarelix acetate is a synthetic third generation gonadotropin-releasing hormone receptor (GnRHR) antagonist. It increases histamine release from rat peritoneal mast cells in vitro and from a human skin model ex vivo. In ... |
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T70775 |
Zoptarelin doxorubicin
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|
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Zoptarelin doxorubicin, also known as AEZS-108, is an LHRH agonist. Zoptarelin doxorubicin is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R) that is conjugated to the anthracycline antibio... |
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T72990 |
BAY 1214784
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BAY 1214784, a potent, selective, and orally active spiroindoline derivative compound, serves as an antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). It notably reduces plasma luteinizing hormone... |
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T81485 |
Phoenixin-14 TFA
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PNX-14 TFA |
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Phoenixin-14 TFA (PNX-14) is a blood-brain barrier (BBB)-penetrable neuropeptide with anxiolytic, cardioprotective, and neuroprotective properties. It modulates pituitary gonadotrophin release by enhancing gonadotropin-r... |
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T76047 |
TAK-683 TFA
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TAK-683 TFA, a potent full KISS1 receptor (KISS1R) agonist with a half-maximal inhibitory concentration (IC50) of 170 pM, exhibits enhanced metabolic stability. As a nonapeptide metastin analog, it demonstrates agonistic... |
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T35794 |
Kisspeptin-54 (human) (trifluoroacetate salt)
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Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gen... |
